The Top 6 CoQ10 Supplements For Longevity
Coenzyme Q10 (CoQ10) is a powerful antioxidant for human health. It helps support heart and brain health, protects against mitochondrial dysfunction and cognitive decline, and is essential for cellular energy production. Unfortunately, the production of this vital compound decreases with age – something that can lead to various health problems if we don't get enough in our diet or supplement properly.
Keeping healthy levels of CoQ10 can support a vibrant lifestyle filled with energy, focus, and long-term wellness. You deserve to feel your best as you age—it all starts with nurturing yourself.
Keep reading to learn more about the best CoQ10 supplements.
My Selection Process
CoQ10 is an essential nutrient for your health. I have done extensive research and selected the best CoQ10 supplements on the market. All supplements included in this article are tested rigorously for ingredient potency and contaminants like heavy metals and microbes.
By reading my comprehensive guide to the best CoQ10 supplements, you'll learn everything you need to know about this important antioxidant. You'll be able to make an informed decision about whether or not CoQ10 supplements are right for you.
Quicksilver Scientific Nanoemulsified CoQ10
Best for cardiovascular health and aging support.
Why I Dig It
Rejuvenate your cells with Quicksilver Scientific's Nanoemulsified CoQ10. This vegan, soy-free, gluten-free, and non-GMO supplement is grounded in science, so you can feel confident about the product you're putting in your body.
CoQ10 helps produce energy on a molecular level, so giving your cells an extra boost can support overall health while promoting healthy aging. Two pumps of the liquid liposomal CoQ10 deliver over 30 mg of CoQ10 per serving. Unlike other CoQ10 supplements, Quicksilver Scientific uses advanced liposomal delivery to allow for direct bloodstream absorption and provide maximum effectiveness.
The Data Dump
Quicksilver Scientific uses cGMP-certified manufacturing processes, ensuring all products meet the regulations of the FDA. They understand that quality and safety are essential to their customers, so they perform in-house and third-party testing on all products.
The tests they conduct look for pesticides, herbicides, solvents, and heavy metals, giving you peace of mind that Quicksilver Scientific provides high quality products with the best results possible.
In addition, Certificates of Analysis are available upon request. With Quicksilver Scientific Nanoemulsified CoQ10, you can be sure you're getting a quality supplement.
Thorne CoQ10
Best for cognition and cardiovascular health.
Why I Dig It
Thorne's CoQ10 promotes healthier aging by supporting cardiovascular and neurological health, cellular energy production, and more! This proprietary, lipid-based, non-crystalline form of coenzyme Q10 is approximately three times better absorbed than ubiquinol, so you're getting superior absorption. The gluten- and dairy-free capsules offer 100 mg of CoQ10 per serving.
The Data Dump
Thorne CoQ10 is the perfect health supplement for those who care about quality and safety. Thorne takes extra caution to ensure each product meets the exact standards in the manufacturing process. They perform comprehensive testing at every stage of production to guarantee that no unwanted contaminants find their way into your capsules.
Before manufacturing begins, they analyze each raw material for identity, quality, purity, and potency. And throughout the process, they check for stability, microbial contamination, and pesticide residues.
Exciting news! While Throne hasn't yet provided Certificates of Analysis, they're working on making these accessible on their website. Keep your eyes peeled for this much-anticipated update, which is projected to be available in 2023.
Bulletproof CoQ10 Energy
Best for cellular energy production and antioxidant support.
Why I Dig It
Bulletproof CoQ10 Energy is packed with 100 mg of CoQ10, 10 mg of PQQ (a compound that works with CoQ10 to support cellular energy production), and 300 mg of Bulletproof Brain Octane MCT Oil (coconut oil helps with absorption of CoQ10).
This formula can boost energy, so you maintain a high level of productivity and have mental clarity. Plus, it's naturally sugar-free, gluten-free, non-GMO, and soy-free.
With powerful antioxidants and compounds that support healthy mitochondrial and cellular energy production, you can feel confident knowing this CoQ10 supplement has you covered during demanding days at work.
The Data Dump
Each ingredient used in Bulletproof products is submitted to standardized quality assurance testing and must pass stringent standards for heavy metals and other toxins. All of their products are developed and manufactured using Good Manufacturing Practice-certified facilities. Bulletproof does not provide Certificates of Analysis because it contains information that is considered proprietary.
Bulletproof CoQ 10 Energy is well known for providing optimal antioxidant support. You'll love having the increased energy it brings in all areas of your life.
Pure Encapsulations CoQ10
Best for enhanced energy and cardiovascular support.
Why I Dig It
Pure Encapsulations CoQ10 will provide cellular energy and protect against free radicals while promoting cardiovascular health. This supplement contains 100% trans-isomer, derived from natural fermentation, and provides 250 mg of CoQ10 per serving. Pure Encapsulations ingredients are sourced from trusted suppliers, and all products are free of wheat, peanuts, eggs, and GMOs and contain no artificial colors, flavors or sweeteners.
The Data Dump
Pure Encapsulations supplements are made from pure ingredients free from common allergens and rigorously tested by independent laboratories for efficacy and safety. In addition, their labs are Good Manufacturing Practice-certified (cGMP), meaning they are held to the highest production and quality control standards. With this product, you can rest assured you're using a safe and natural supplement for your health needs. I use several of their products which my naturopathic doctor recommended.
Furthermore, Pure Encapsulations has begun an innovative partnership with TerraCycle to promote sustainability and environmental responsibility. Their goal is to reduce plastic waste by allowing customers to send back any used Pure Encapsulation packaging for recycling, resulting in fewer containers going into landfills. A Certificate of Analysis (CoA) will also be provided upon request just send them an email.
Designs for Health CoQNOL 200
Best for anti-aging support and cardiovascular health.
Why I Dig It
This unique CoQ10 supplement combines ubiquinol and trans-geranylgeraniol (GG-Gold), a perfect way to optimize your well-being. Every serving comes packed with 100 mg of ubiquinol and 60 mg GG extract from annatto seeds, which enhances absorption and supports endogenous CoQ10 synthesis. It's also gluten-free, dairy-free, soy-free, and non-GMO. It is recommended to take one soft gel a day with a meal.
The Data Dump
Designs for Health is a top-tier quality nutritional supplement company embodying the highest manufacturing and testing protocol standards. All ingredients are carefully sourced, tested, and developed to provide you with high-quality supplements that will help enhance your health. Designs for Health products are third-party tested for purity, strength, and quality, as well as for pesticides, heavy metals, and microbiological organisms. Also, all testing adheres to FDA Good Manufacturing Practices.
I contacted the company about providing Certificates of Analysis (CoA) and they informed me that CoA's can be requested through your healthcare practitioner. When you purchase Designs for Health CoQNOL 200, you can rest assured knowing you're getting a product that will deliver on its promise to contribute to improved health benefits.
MaryRuth’s Liquid CoQ10
Best for mitochondrial and immune support.
Why I Dig It
MaryRuth's Liquid CoQ10 is a tasty and fun way to get essential vitamins and minerals! This liposomal CoQ10 supplement is conveniently packed into a liquid form, making it easy to add straight into your favorite beverage or food. This supplement can support the heart and immune system through its state-of-the-art micelle liposomal delivery system. Micelle liposomal delivery encapsulates the vitamin/nutrients into tiny micelles before they become enveloped in liposomes. These little protective pockets allow for superior absorption by the gut, so you reap maximum benefits.
This creamy CoQ10 formulation has a sweet citrus peach taste and offers 75 mg per serving of ubiquinone. This supplement is vegan, non-GMO, and free from dairy, gluten, wheat, soy, corn, nightshades, added sugars, and artificial colors.
The Data Dump
At MaryRuth's, quality and safety are their top priorities. To ensure the safety and integrity of the product you receive, MaryRuth's employs ISO 17025-certified labs for rigorous third-party testing to guarantee their supplements are free from contaminants such as microbes and heavy metals. Not only that but MaryRuth's also earned certification from the Clean Label Project, which focuses on hazardous environmental toxins in consumer goods.
Currently, MaryRuth's does not share Certificates of Analysis (CoA). However, they told me that they believe transparency is essential and are actively reviewing their processes around sharing safety data with customers.
Additionally, they use Prop 65 parameters for heavy metal testing to ensure top-tier results. Every Certificate of Analysis must pass through their strict standards before they can even bring it to market — so you can trust that when you buy from MaryRuth's, you're getting only the best.
Benefits of CoQ10 Supplementation
Coenzyme Q10 (CoQ10) is a fat-soluble antioxidant naturally produced in the human body and plays an essential role in synthesizing cellular energy. CoQ10 exists in the oxidized form, ubiquinone, and the reduced form, ubiquinol. Numerous factors including genetics, aging, and statin medications, can cause a decrease in CoQ10 levels within the body. As we age, our body's ability to make its own CoQ10 decreases, and this begins to decline in our twenties!
This is a concerning issue, as deficiencies in this essential compound are linked to many health conditions ranging from neurodegenerative disorders to cardiovascular disease. Maintaining optimal CoQ10 concentrations is critical for overall health and well-being.
CoQ10 can be found in fruits, vegetables, meat, fish, nuts, and oils containing about 10-50 mg/kg. However, animal livers and hearts have the highest amount, ~30-200 mg/kg. While a well-rounded diet may provide adequate levels of CoQ10, supplementation of CoQ10 offers a means to maintain proper levels within the body.
A meta-analysis in 2018 examined randomized controlled trials and the effect of CoQ10 supplementation on blood pressure in patients with metabolic syndrome. The review concluded that CoQ10 supplements may reduce systolic blood pressure without changing diastolic blood pressure. Additionally, CoQ10 supplements showed some promise for slowing the progression of Parkinson's disease in the early stage. Some studies have even found improved oral and gum health when CoQ10 was applied topically.
Thanks to CoQ10's strong antioxidant activity and role in energy production in the mitochondria, it has been considered a potential candidate for treating cardiovascular disease (i.e., heart failure, congestive heart failure, hypertension), neurodegenerative disorders, diabetes, and cancer. CoQ10 supplements can increase cognitive function, reduce oxidative stress, improve exercise capacity, and even slow the effects of aging.
CoQ10 FAQs
Many people are interested in CoQ10 supplements, but they're still determining if they should take them. They also have a lot of questions about CoQ10 that need answering.
Do you start with a low dose and work your way up? What's the best time of day to take CoQ10 supplements? How long do you need to take them?
I have extensively researched the best answers to common questions about CoQ10. My mission is to arm you with comprehensive knowledge so that you can make well-informed decisions about your health journey!
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CoQ10 exists within the body in two forms: the oxidized form, ubiquinone, and the reduced form, ubiquinol. Many believe that ubiquinol is better absorbed than ubiquinone. However, several clinical studies have reported no significant difference in the absorption of ubiquinone and ubiquinol supplements in healthy volunteers.
Additionally, intestinal absorption of CoQ10 is highly variable, regardless of whether participants consumed ubiquinone or ubiquinol supplements. This is because the body is limited in how much CoQ10 it can absorb at any given time. Thus, splitting the CoQ10 doses across the day is recommended to maximize absorption. Also, you may consider taking the capsules after you have eaten a meal with "healthy fats" to further support absorption. -
Yes, it is absolutely fine to take CoQ10 every day. Daily supplementation with CoQ10 has been linked to numerous benefits, such as increased energy levels, improved mental focus and concentration, better digestion, and fewer headaches.
Studies show that daily supplementation can also support healthy blood pressure levels by improving vasodilation of the arteries, which allows for more efficient nutrient delivery throughout the body. Additionally, daily doses can help protect against oxidative stress caused by free radicals in the environment as well as protect cells from damage due to aging. Overall, make sure you split up your doses to maximize the absorption of CoQ10. -
The recommended dose for most healthy adults varies depending on the indication but is usually around 30-100 mg. However, the dose can be increased up to 60-1,200 mg for specific medical conditions.
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Yes, CoQ10 is worth taking because of its many potential health benefits. It plays an essential role in producing cellular energy and protecting cells from oxidative damage caused by free radicals. Studies have shown that supplementation with CoQ10 can support healthy blood pressure levels and reduce the symptoms of some chronic conditions like heart disease, high cholesterol, and diabetes. It may also improve athletic performance and fertility outcomes.
Additionally, it has been linked to improved energy metabolism and helps fight fatigue associated with aging. Furthermore, preliminary studies have suggested that CoQ10 may also have antioxidant properties that help boost the immune system and protect against certain forms of cancer. -
The most common symptoms of low CoQ10 include fatigue or exhaustion even after sleeping for long intervals, muscle weakness, headaches, impaired thinking or memory loss, exercise intolerance and shortness of breath during activity, mood swings/depression/anxiety attacks, and a weakened immune system. In some cases, supplementation may be recommended - either through food sources or CoQ10 supplements.
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Vitamin E intake may interfere with CoQ10 absorption; thus, consider taking vitamin E at a different time during the day. Medications such as beta blockers and statins may interact with your CoQ10 supplement. Ultimately, those on prescription drugs may consult their doctor before starting a CoQ10 supplement.
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Splitting the CoQ10 doses across the day is recommended to maximize absorption because the body is limited in how much CoQ10 it can absorb at any given time.
The presence of fat enhances CoQ10 absorption. Thus, taking CoQ10 with meals containing fat or finding a supplement brand that encapsulates CoQ10 within a suitable delivery system is recommended. -
The short answer is no; CoQ10 is not hard on the liver. Research shows that CoQ10 can be beneficial to liver health. It can help protect the liver from oxidative stress. Additionally, studies have found that CoQ10 supplementation can help boost mitochondrial energy production in hepatocytes (liver cells), which aids overall digestive functioning.
A 2016 study looked at the effects of CoQ10 supplementation on markers of liver function over 12 weeks. The study concluded that CoQ10 supplementation of 100 mg could improve systemic inflammation in patients with nonalcoholic fatty liver disease. -
Taking CoQ10 may have a protective effect on risk factors such as atherosclerosis. Its antiatherosclerotic mechanism of action may be related to its antioxidant properties. CoQ10 has positively affected heart performance in patients with congestive heart failure and ischemic heart disease.
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CoQ10 and fish oil provide nutritional benefits for the heart, but how they benefit the cardiovascular system depends on their respective roles. CoQ10 is a naturally occurring vitamin-like compound found in every cell of the human body, primarily in organs like the heart that use large amounts of energy. It is essential to mitochondrial function, which powers your cells with energy and maintains proper cell structure and metabolism.
High levels of CoQ10 have been shown to help reduce blood pressure, improve blood sugar control, and enhance exercise endurance. It also helps protect against damage from oxidative stress caused by free radicals - molecules that can cause cellular damage if left unchecked - so it's particularly beneficial for those with increased risks due to high cholesterol or diabetes.
Fish oil is rich in omega-3 fatty acids EPA and DHA, essential nutrients necessary for healthy cell structure and function throughout your entire body, including heart muscle cells. Omega 3 fatty acids are anti-inflammatory fats that support heart health. Overall, CoQ10 and fish oil offer immense benefits when protecting our hearts - that's why I take CoQ10 and fish oil supplements. -
CoQ10 supplementation is safe and well-tolerated at doses much higher than usual, with few drug interactions and minor side effects. The most common reported side effects of CoQ10 are digestive issues, but this was observed when doses increased beyond 1,200 mg/day. However, the safety in children or women who are pregnant or lactating has not been established.
The Recap
Overall, supplementing with CoQ10 is a great way to protect your heart and prevent harmful diseases. While there are many supplements on the market, choosing what is best for you is important.
Hopefully, this blog post has given you an informed perspective on the subject by highlighting some of the benefits of CoQ10. To further research your options, feel free to peruse my list of the best CoQ10 supplements. Remember these essentials, and don't hesitate to contact companies with questions or concerns.
At the end of the day, health is wealth. Investing in yourself pays off in dividends, as taking care of your body now will improve your health and life span! Thank you again for taking time out of your day to read my blog post.
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